Dolantin
Dolantin Brand names, Dolantin Analogs
Dolantin Brand Names Mixture
- No information avaliable
Dolantin Chemical_Formula
C15H21NO2
Dolantin RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Dolantin fda sheet
Dolantin msds (material safety sheet)
Dolantin Synthesis Reference
No information avaliable
Dolantin Molecular Weight
247.333 g/mol
Dolantin Melting Point
186 - 189 oC
Dolantin H2O Solubility
3220 mg/L
Dolantin State
Solid
Dolantin LogP
3.303
Dolantin Dosage Forms
Syrup; Tablet
Dolantin Indication
Used to control moderate to severe pain.
Dolantin Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Dolantin Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Dolantin side effects and Toxicity
No information avaliable
Dolantin Patient Information
No information avaliable
Dolantin Organisms Affected
Humans and other mammals
