Demerol
Demerol Brand names, Demerol Analogs
Demerol Brand Names Mixture
- No information avaliable
Demerol Chemical_Formula
C15H21NO2
Demerol RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Demerol fda sheet
Demerol msds (material safety sheet)
Demerol Synthesis Reference
No information avaliable
Demerol Molecular Weight
247.333 g/mol
Demerol Melting Point
186 - 189 oC
Demerol H2O Solubility
3220 mg/L
Demerol State
Solid
Demerol LogP
3.303
Demerol Dosage Forms
Syrup; Tablet
Demerol Indication
Used to control moderate to severe pain.
Demerol Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Demerol Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Demerol side effects and Toxicity
No information avaliable
Demerol Patient Information
No information avaliable
Demerol Organisms Affected
Humans and other mammals
