Dispadol
Brand names,
Dispadol
Analogs
Dispadol
Brand Names Mixture
Dispadol
Chemical_Formula
C15H21NO2
Dispadol
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Dispadol
fda sheet
Dispadol
msds (material safety sheet)
Dispadol
Synthesis Reference
No information avaliable
Dispadol
Molecular Weight
247.333 g/mol
Dispadol
Melting Point
186 - 189 oC
Dispadol
H2O Solubility
3220 mg/L
Dispadol
State
Solid
Dispadol
LogP
3.303
Dispadol
Dosage Forms
Syrup; Tablet
Dispadol
Indication
Used to control moderate to severe pain.
Dispadol
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Dispadol
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Dispadol
side effects and Toxicity
No information avaliable
Dispadol
Patient Information
No information avaliable
Dispadol
Organisms Affected
Humans and other mammals