Dolsin
Dolsin Brand names, Dolsin Analogs
Dolsin Brand Names Mixture
- No information avaliable
Dolsin Chemical_Formula
C15H21NO2
Dolsin RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Dolsin fda sheet
Dolsin msds (material safety sheet)
Dolsin Synthesis Reference
No information avaliable
Dolsin Molecular Weight
247.333 g/mol
Dolsin Melting Point
186 - 189 oC
Dolsin H2O Solubility
3220 mg/L
Dolsin State
Solid
Dolsin LogP
3.303
Dolsin Dosage Forms
Syrup; Tablet
Dolsin Indication
Used to control moderate to severe pain.
Dolsin Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Dolsin Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Dolsin side effects and Toxicity
No information avaliable
Dolsin Patient Information
No information avaliable
Dolsin Organisms Affected
Humans and other mammals
