Piperosal
Brand names,
Piperosal
Analogs
Piperosal
Brand Names Mixture
Piperosal
Chemical_Formula
C15H21NO2
Piperosal
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Piperosal
fda sheet
Piperosal
msds (material safety sheet)
Piperosal
Synthesis Reference
No information avaliable
Piperosal
Molecular Weight
247.333 g/mol
Piperosal
Melting Point
186 - 189 oC
Piperosal
H2O Solubility
3220 mg/L
Piperosal
State
Solid
Piperosal
LogP
3.303
Piperosal
Dosage Forms
Syrup; Tablet
Piperosal
Indication
Used to control moderate to severe pain.
Piperosal
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Piperosal
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Piperosal
side effects and Toxicity
No information avaliable
Piperosal
Patient Information
No information avaliable
Piperosal
Organisms Affected
Humans and other mammals