Phetidine
Phetidine Brand names, Phetidine Analogs
Phetidine Brand Names Mixture
- No information avaliable
Phetidine Chemical_Formula
C15H21NO2
Phetidine RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Phetidine fda sheet
Phetidine msds (material safety sheet)
Phetidine Synthesis Reference
No information avaliable
Phetidine Molecular Weight
247.333 g/mol
Phetidine Melting Point
186 - 189 oC
Phetidine H2O Solubility
3220 mg/L
Phetidine State
Solid
Phetidine LogP
3.303
Phetidine Dosage Forms
Syrup; Tablet
Phetidine Indication
Used to control moderate to severe pain.
Phetidine Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Phetidine Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Phetidine side effects and Toxicity
No information avaliable
Phetidine Patient Information
No information avaliable
Phetidine Organisms Affected
Humans and other mammals
