Meperidol
Meperidol Brand names, Meperidol Analogs
Meperidol Brand Names Mixture
- No information avaliable
Meperidol Chemical_Formula
C15H21NO2
Meperidol RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Meperidol fda sheet
Meperidol msds (material safety sheet)
Meperidol Synthesis Reference
No information avaliable
Meperidol Molecular Weight
247.333 g/mol
Meperidol Melting Point
186 - 189 oC
Meperidol H2O Solubility
3220 mg/L
Meperidol State
Solid
Meperidol LogP
3.303
Meperidol Dosage Forms
Syrup; Tablet
Meperidol Indication
Used to control moderate to severe pain.
Meperidol Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Meperidol Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Meperidol side effects and Toxicity
No information avaliable
Meperidol Patient Information
No information avaliable
Meperidol Organisms Affected
Humans and other mammals
