Demarol
Demarol Brand names, Demarol Analogs
Demarol Brand Names Mixture
- No information avaliable
Demarol Chemical_Formula
C15H21NO2
Demarol RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Demarol fda sheet
Demarol msds (material safety sheet)
Demarol Synthesis Reference
No information avaliable
Demarol Molecular Weight
247.333 g/mol
Demarol Melting Point
186 - 189 oC
Demarol H2O Solubility
3220 mg/L
Demarol State
Solid
Demarol LogP
3.303
Demarol Dosage Forms
Syrup; Tablet
Demarol Indication
Used to control moderate to severe pain.
Demarol Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Demarol Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Demarol side effects and Toxicity
No information avaliable
Demarol Patient Information
No information avaliable
Demarol Organisms Affected
Humans and other mammals
