Petantin
Brand names,
Petantin
Analogs
Petantin
Brand Names Mixture
Petantin
Chemical_Formula
C15H21NO2
Petantin
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Petantin
fda sheet
Petantin
msds (material safety sheet)
Petantin
Synthesis Reference
No information avaliable
Petantin
Molecular Weight
247.333 g/mol
Petantin
Melting Point
186 - 189 oC
Petantin
H2O Solubility
3220 mg/L
Petantin
State
Solid
Petantin
LogP
3.303
Petantin
Dosage Forms
Syrup; Tablet
Petantin
Indication
Used to control moderate to severe pain.
Petantin
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Petantin
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Petantin
side effects and Toxicity
No information avaliable
Petantin
Patient Information
No information avaliable
Petantin
Organisms Affected
Humans and other mammals