Pipersal
Brand names,
Pipersal
Analogs
Pipersal
Brand Names Mixture
Pipersal
Chemical_Formula
C15H21NO2
Pipersal
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Pipersal
fda sheet
Pipersal
msds (material safety sheet)
Pipersal
Synthesis Reference
No information avaliable
Pipersal
Molecular Weight
247.333 g/mol
Pipersal
Melting Point
186 - 189 oC
Pipersal
H2O Solubility
3220 mg/L
Pipersal
State
Solid
Pipersal
LogP
3.303
Pipersal
Dosage Forms
Syrup; Tablet
Pipersal
Indication
Used to control moderate to severe pain.
Pipersal
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Pipersal
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Pipersal
side effects and Toxicity
No information avaliable
Pipersal
Patient Information
No information avaliable
Pipersal
Organisms Affected
Humans and other mammals