Isonipecaine
Brand names,
Isonipecaine
Analogs
Isonipecaine
Brand Names Mixture
Isonipecaine
Chemical_Formula
C15H21NO2
Isonipecaine
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Isonipecaine
fda sheet
Isonipecaine
msds (material safety sheet)
Isonipecaine
Synthesis Reference
No information avaliable
Isonipecaine
Molecular Weight
247.333 g/mol
Isonipecaine
Melting Point
186 - 189 oC
Isonipecaine
H2O Solubility
3220 mg/L
Isonipecaine
State
Solid
Isonipecaine
LogP
3.303
Isonipecaine
Dosage Forms
Syrup; Tablet
Isonipecaine
Indication
Used to control moderate to severe pain.
Isonipecaine
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Isonipecaine
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Isonipecaine
side effects and Toxicity
No information avaliable
Isonipecaine
Patient Information
No information avaliable
Isonipecaine
Organisms Affected
Humans and other mammals