Meperidine Hcl
Brand names,
Meperidine Hcl
Analogs
Meperidine Hcl
Brand Names Mixture
Meperidine Hcl
Chemical_Formula
C15H21NO2
Meperidine Hcl
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Meperidine Hcl
fda sheet
Meperidine Hcl
msds (material safety sheet)
Meperidine Hcl
Synthesis Reference
No information avaliable
Meperidine Hcl
Molecular Weight
247.333 g/mol
Meperidine Hcl
Melting Point
186 - 189 oC
Meperidine Hcl
H2O Solubility
3220 mg/L
Meperidine Hcl
State
Solid
Meperidine Hcl
LogP
3.303
Meperidine Hcl
Dosage Forms
Syrup; Tablet
Meperidine Hcl
Indication
Used to control moderate to severe pain.
Meperidine Hcl
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Meperidine Hcl
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Meperidine Hcl
side effects and Toxicity
No information avaliable
Meperidine Hcl
Patient Information
No information avaliable
Meperidine Hcl
Organisms Affected
Humans and other mammals