Pethidin
Pethidin Brand names, Pethidin Analogs
Pethidin Brand Names Mixture
- No information avaliable
Pethidin Chemical_Formula
C15H21NO2
Pethidin RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Pethidin fda sheet
Pethidin msds (material safety sheet)
Pethidin Synthesis Reference
No information avaliable
Pethidin Molecular Weight
247.333 g/mol
Pethidin Melting Point
186 - 189 oC
Pethidin H2O Solubility
3220 mg/L
Pethidin State
Solid
Pethidin LogP
3.303
Pethidin Dosage Forms
Syrup; Tablet
Pethidin Indication
Used to control moderate to severe pain.
Pethidin Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Pethidin Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Pethidin side effects and Toxicity
No information avaliable
Pethidin Patient Information
No information avaliable
Pethidin Organisms Affected
Humans and other mammals
