Pethidineter
Brand names,
Pethidineter
Analogs
Pethidineter
Brand Names Mixture
Pethidineter
Chemical_Formula
C15H21NO2
Pethidineter
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Pethidineter
fda sheet
Pethidineter
msds (material safety sheet)
Pethidineter
Synthesis Reference
No information avaliable
Pethidineter
Molecular Weight
247.333 g/mol
Pethidineter
Melting Point
186 - 189 oC
Pethidineter
H2O Solubility
3220 mg/L
Pethidineter
State
Solid
Pethidineter
LogP
3.303
Pethidineter
Dosage Forms
Syrup; Tablet
Pethidineter
Indication
Used to control moderate to severe pain.
Pethidineter
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Pethidineter
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Pethidineter
side effects and Toxicity
No information avaliable
Pethidineter
Patient Information
No information avaliable
Pethidineter
Organisms Affected
Humans and other mammals