Petydyna
Brand names,
Petydyna
Analogs
Petydyna
Brand Names Mixture
Petydyna
Chemical_Formula
C15H21NO2
Petydyna
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Petydyna
fda sheet
Petydyna
msds (material safety sheet)
Petydyna
Synthesis Reference
No information avaliable
Petydyna
Molecular Weight
247.333 g/mol
Petydyna
Melting Point
186 - 189 oC
Petydyna
H2O Solubility
3220 mg/L
Petydyna
State
Solid
Petydyna
LogP
3.303
Petydyna
Dosage Forms
Syrup; Tablet
Petydyna
Indication
Used to control moderate to severe pain.
Petydyna
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Petydyna
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Petydyna
side effects and Toxicity
No information avaliable
Petydyna
Patient Information
No information avaliable
Petydyna
Organisms Affected
Humans and other mammals