Operidine
Operidine Brand names, Operidine Analogs
Operidine Brand Names Mixture
- No information avaliable
Operidine Chemical_Formula
C15H21NO2
Operidine RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Operidine fda sheet
Operidine msds (material safety sheet)
Operidine Synthesis Reference
No information avaliable
Operidine Molecular Weight
247.333 g/mol
Operidine Melting Point
186 - 189 oC
Operidine H2O Solubility
3220 mg/L
Operidine State
Solid
Operidine LogP
3.303
Operidine Dosage Forms
Syrup; Tablet
Operidine Indication
Used to control moderate to severe pain.
Operidine Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Operidine Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Operidine side effects and Toxicity
No information avaliable
Operidine Patient Information
No information avaliable
Operidine Organisms Affected
Humans and other mammals
