Centralgin
Centralgin Brand names, Centralgin Analogs
Centralgin Brand Names Mixture
- No information avaliable
Centralgin Chemical_Formula
C15H21NO2
Centralgin RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Centralgin fda sheet
Centralgin msds (material safety sheet)
Centralgin Synthesis Reference
No information avaliable
Centralgin Molecular Weight
247.333 g/mol
Centralgin Melting Point
186 - 189 oC
Centralgin H2O Solubility
3220 mg/L
Centralgin State
Solid
Centralgin LogP
3.303
Centralgin Dosage Forms
Syrup; Tablet
Centralgin Indication
Used to control moderate to severe pain.
Centralgin Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Centralgin Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Centralgin side effects and Toxicity
No information avaliable
Centralgin Patient Information
No information avaliable
Centralgin Organisms Affected
Humans and other mammals
