Nemerol
Brand names,
Nemerol
Analogs
Nemerol
Brand Names Mixture
Nemerol
Chemical_Formula
C15H21NO2
Nemerol
RX_link
http://www.rxlist.com/cgi/generic/meper.htm
Nemerol
fda sheet
Nemerol
msds (material safety sheet)
Nemerol
Synthesis Reference
No information avaliable
Nemerol
Molecular Weight
247.333 g/mol
Nemerol
Melting Point
186 - 189 oC
Nemerol
H2O Solubility
3220 mg/L
Nemerol
State
Solid
Nemerol
LogP
3.303
Nemerol
Dosage Forms
Syrup; Tablet
Nemerol
Indication
Used to control moderate to severe pain.
Nemerol
Pharmacology
Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.
Nemerol
Absorption
Oral bioavailability is 50-60% in patients with normal hepatic function.
Nemerol
side effects and Toxicity
No information avaliable
Nemerol
Patient Information
No information avaliable
Nemerol
Organisms Affected
Humans and other mammals