Furazolidone
Brand names,
Furazolidone
Analogs
Furazolidone
Brand Names Mixture
Furazolidone
Chemical_Formula
C8H7N3O5
Furazolidone
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furazolidone
fda sheet
Furazolidone
msds (material safety sheet)
Furazolidone
Synthesis Reference
No information avaliable
Furazolidone
Molecular Weight
225.158 g/mol
Furazolidone
Melting Point
255 oC
Furazolidone
H2O Solubility
40 mg/L
Furazolidone
State
Solid
Furazolidone
LogP
0.691
Furazolidone
Dosage Forms
Tablets; Liquid
Furazolidone
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furazolidone
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furazolidone
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furazolidone
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furazolidone
Patient Information
No information avaliable
Furazolidone
Organisms Affected
Microbes (bacteria, parasites)