Nifurazolidone

Nifurazolidone Brand names, Nifurazolidone Analogs

Nifurazolidone Brand Names Mixture

No information avaliable

Nifurazolidone Chemical_Formula

C₈H₇N₃O₅

Nifurazolidone RX_link

http://www.rxlist.com/cgi/generic2/furazol.htm

Nifurazolidone fda sheet

Nifurazolidone msds (material safety sheet)

Nifurazolidone MSDS

Nifurazolidone Synthesis Reference

No information avaliable

Nifurazolidone Molecular Weight

225.158 g/mol

Nifurazolidone Melting Point

255 ^oC

Nifurazolidone H₂O Solubility

40 mg/L

Nifurazolidone State

Solid

Nifurazolidone LogP

0.691

Nifurazolidone Dosage Forms

Tablets; Liquid

Nifurazolidone Indication

For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.

Nifurazolidone Pharmacology

Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.

Nifurazolidone Absorption

Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration

Nifurazolidone side effects and Toxicity

Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.

Nifurazolidone Patient Information