Furaxone
Brand names,
Furaxone
Analogs
Furaxone
Brand Names Mixture
Furaxone
Chemical_Formula
C8H7N3O5
Furaxone
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furaxone
fda sheet
Furaxone
msds (material safety sheet)
Furaxone
Synthesis Reference
No information avaliable
Furaxone
Molecular Weight
225.158 g/mol
Furaxone
Melting Point
255 oC
Furaxone
H2O Solubility
40 mg/L
Furaxone
State
Solid
Furaxone
LogP
0.691
Furaxone
Dosage Forms
Tablets; Liquid
Furaxone
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furaxone
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furaxone
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furaxone
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furaxone
Patient Information
No information avaliable
Furaxone
Organisms Affected
Microbes (bacteria, parasites)