Furozolidine
Brand names,
Furozolidine
Analogs
Furozolidine
Brand Names Mixture
Furozolidine
Chemical_Formula
C8H7N3O5
Furozolidine
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furozolidine
fda sheet
Furozolidine
msds (material safety sheet)
Furozolidine
Synthesis Reference
No information avaliable
Furozolidine
Molecular Weight
225.158 g/mol
Furozolidine
Melting Point
255 oC
Furozolidine
H2O Solubility
40 mg/L
Furozolidine
State
Solid
Furozolidine
LogP
0.691
Furozolidine
Dosage Forms
Tablets; Liquid
Furozolidine
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furozolidine
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furozolidine
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furozolidine
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furozolidine
Patient Information
No information avaliable
Furozolidine
Organisms Affected
Microbes (bacteria, parasites)