Nifulidone
Brand names,
Nifulidone
Analogs
Nifulidone
Brand Names Mixture
Nifulidone
Chemical_Formula
C8H7N3O5
Nifulidone
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Nifulidone
fda sheet
Nifulidone
msds (material safety sheet)
Nifulidone
Synthesis Reference
No information avaliable
Nifulidone
Molecular Weight
225.158 g/mol
Nifulidone
Melting Point
255 oC
Nifulidone
H2O Solubility
40 mg/L
Nifulidone
State
Solid
Nifulidone
LogP
0.691
Nifulidone
Dosage Forms
Tablets; Liquid
Nifulidone
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Nifulidone
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Nifulidone
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Nifulidone
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Nifulidone
Patient Information
No information avaliable
Nifulidone
Organisms Affected
Microbes (bacteria, parasites)