Nitrofurazolidone
Brand names,
Nitrofurazolidone
Analogs
Nitrofurazolidone
Brand Names Mixture
Nitrofurazolidone
Chemical_Formula
C8H7N3O5
Nitrofurazolidone
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Nitrofurazolidone
fda sheet
Nitrofurazolidone
msds (material safety sheet)
Nitrofurazolidone
Synthesis Reference
No information avaliable
Nitrofurazolidone
Molecular Weight
225.158 g/mol
Nitrofurazolidone
Melting Point
255 oC
Nitrofurazolidone
H2O Solubility
40 mg/L
Nitrofurazolidone
State
Solid
Nitrofurazolidone
LogP
0.691
Nitrofurazolidone
Dosage Forms
Tablets; Liquid
Nitrofurazolidone
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Nitrofurazolidone
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Nitrofurazolidone
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Nitrofurazolidone
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Nitrofurazolidone
Patient Information
No information avaliable
Nitrofurazolidone
Organisms Affected
Microbes (bacteria, parasites)