Nitrofuroxon
Brand names,
Nitrofuroxon
Analogs
Nitrofuroxon
Brand Names Mixture
Nitrofuroxon
Chemical_Formula
C8H7N3O5
Nitrofuroxon
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Nitrofuroxon
fda sheet
Nitrofuroxon
msds (material safety sheet)
Nitrofuroxon
Synthesis Reference
No information avaliable
Nitrofuroxon
Molecular Weight
225.158 g/mol
Nitrofuroxon
Melting Point
255 oC
Nitrofuroxon
H2O Solubility
40 mg/L
Nitrofuroxon
State
Solid
Nitrofuroxon
LogP
0.691
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Dosage Forms
Tablets; Liquid
Nitrofuroxon
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Nitrofuroxon
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Nitrofuroxon
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Nitrofuroxon
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Nitrofuroxon
Patient Information
No information avaliable
Nitrofuroxon
Organisms Affected
Microbes (bacteria, parasites)