Furazolidine
Brand names,
Furazolidine
Analogs
Furazolidine
Brand Names Mixture
Furazolidine
Chemical_Formula
C8H7N3O5
Furazolidine
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furazolidine
fda sheet
Furazolidine
msds (material safety sheet)
Furazolidine
Synthesis Reference
No information avaliable
Furazolidine
Molecular Weight
225.158 g/mol
Furazolidine
Melting Point
255 oC
Furazolidine
H2O Solubility
40 mg/L
Furazolidine
State
Solid
Furazolidine
LogP
0.691
Furazolidine
Dosage Forms
Tablets; Liquid
Furazolidine
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furazolidine
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furazolidine
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furazolidine
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furazolidine
Patient Information
No information avaliable
Furazolidine
Organisms Affected
Microbes (bacteria, parasites)