Topazone

Topazone Brand names, Topazone Analogs

Topazone Brand Names Mixture

No information avaliable

Topazone Chemical_Formula

C₈H₇N₃O₅

Topazone RX_link

http://www.rxlist.com/cgi/generic2/furazol.htm

Topazone fda sheet

Topazone msds (material safety sheet)

Topazone MSDS

Topazone Synthesis Reference

No information avaliable

Topazone Molecular Weight

225.158 g/mol

Topazone Melting Point

255 ^oC

Topazone H₂O Solubility

40 mg/L

Topazone State

Solid

Topazone LogP

0.691

Topazone Dosage Forms

Tablets; Liquid

Topazone Indication

For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.

Topazone Pharmacology

Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.

Topazone Absorption

Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration

Topazone side effects and Toxicity

Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.

Topazone Patient Information