Furidon
Brand names,
Furidon
Analogs
Furidon
Brand Names Mixture
Furidon
Chemical_Formula
C8H7N3O5
Furidon
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furidon
fda sheet
Furidon
msds (material safety sheet)
Furidon
Synthesis Reference
No information avaliable
Furidon
Molecular Weight
225.158 g/mol
Furidon
Melting Point
255 oC
Furidon
H2O Solubility
40 mg/L
Furidon
State
Solid
Furidon
LogP
0.691
Furidon
Dosage Forms
Tablets; Liquid
Furidon
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furidon
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furidon
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furidon
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furidon
Patient Information
No information avaliable
Furidon
Organisms Affected
Microbes (bacteria, parasites)