Furox
Brand names,
Furox
Analogs
Furox
Brand Names Mixture
Furox
Chemical_Formula
C8H7N3O5
Furox
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furox
fda sheet
Furox
msds (material safety sheet)
Furox
Synthesis Reference
No information avaliable
Furox
Molecular Weight
225.158 g/mol
Furox
Melting Point
255 oC
Furox
H2O Solubility
40 mg/L
Furox
State
Solid
Furox
LogP
0.691
Furox
Dosage Forms
Tablets; Liquid
Furox
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furox
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furox
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furox
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furox
Patient Information
No information avaliable
Furox
Organisms Affected
Microbes (bacteria, parasites)