Nitrofurazolidonum
Brand names,
Nitrofurazolidonum
Analogs
Nitrofurazolidonum
Brand Names Mixture
Nitrofurazolidonum
Chemical_Formula
C8H7N3O5
Nitrofurazolidonum
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Nitrofurazolidonum
fda sheet
Nitrofurazolidonum
msds (material safety sheet)
Nitrofurazolidonum
Synthesis Reference
No information avaliable
Nitrofurazolidonum
Molecular Weight
225.158 g/mol
Nitrofurazolidonum
Melting Point
255 oC
Nitrofurazolidonum
H2O Solubility
40 mg/L
Nitrofurazolidonum
State
Solid
Nitrofurazolidonum
LogP
0.691
Nitrofurazolidonum
Dosage Forms
Tablets; Liquid
Nitrofurazolidonum
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Nitrofurazolidonum
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Nitrofurazolidonum
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Nitrofurazolidonum
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Nitrofurazolidonum
Patient Information
No information avaliable
Nitrofurazolidonum
Organisms Affected
Microbes (bacteria, parasites)