Furoxane
Brand names,
Furoxane
Analogs
Furoxane
Brand Names Mixture
Furoxane
Chemical_Formula
C8H7N3O5
Furoxane
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Furoxane
fda sheet
Furoxane
msds (material safety sheet)
Furoxane
Synthesis Reference
No information avaliable
Furoxane
Molecular Weight
225.158 g/mol
Furoxane
Melting Point
255 oC
Furoxane
H2O Solubility
40 mg/L
Furoxane
State
Solid
Furoxane
LogP
0.691
Furoxane
Dosage Forms
Tablets; Liquid
Furoxane
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Furoxane
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Furoxane
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Furoxane
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Furoxane
Patient Information
No information avaliable
Furoxane
Organisms Affected
Microbes (bacteria, parasites)