Roptazol
Brand names,
Roptazol
Analogs
Roptazol
Brand Names Mixture
Roptazol
Chemical_Formula
C8H7N3O5
Roptazol
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Roptazol
fda sheet
Roptazol
msds (material safety sheet)
Roptazol
Synthesis Reference
No information avaliable
Roptazol
Molecular Weight
225.158 g/mol
Roptazol
Melting Point
255 oC
Roptazol
H2O Solubility
40 mg/L
Roptazol
State
Solid
Roptazol
LogP
0.691
Roptazol
Dosage Forms
Tablets; Liquid
Roptazol
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Roptazol
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Roptazol
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Roptazol
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Roptazol
Patient Information
No information avaliable
Roptazol
Organisms Affected
Microbes (bacteria, parasites)