Tikofuran
Brand names,
Tikofuran
Analogs
Tikofuran
Brand Names Mixture
Tikofuran
Chemical_Formula
C8H7N3O5
Tikofuran
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Tikofuran
fda sheet
Tikofuran
msds (material safety sheet)
Tikofuran
Synthesis Reference
No information avaliable
Tikofuran
Molecular Weight
225.158 g/mol
Tikofuran
Melting Point
255 oC
Tikofuran
H2O Solubility
40 mg/L
Tikofuran
State
Solid
Tikofuran
LogP
0.691
Tikofuran
Dosage Forms
Tablets; Liquid
Tikofuran
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Tikofuran
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Tikofuran
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Tikofuran
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Tikofuran
Patient Information
No information avaliable
Tikofuran
Organisms Affected
Microbes (bacteria, parasites)