Giarlam
Brand names,
Giarlam
Analogs
Giarlam
Brand Names Mixture
Giarlam
Chemical_Formula
C8H7N3O5
Giarlam
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Giarlam
fda sheet
Giarlam
msds (material safety sheet)
Giarlam
Synthesis Reference
No information avaliable
Giarlam
Molecular Weight
225.158 g/mol
Giarlam
Melting Point
255 oC
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H2O Solubility
40 mg/L
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State
Solid
Giarlam
LogP
0.691
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Dosage Forms
Tablets; Liquid
Giarlam
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Giarlam
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Giarlam
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Giarlam
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Giarlam
Patient Information
No information avaliable
Giarlam
Organisms Affected
Microbes (bacteria, parasites)