Trifurox
Brand names,
Trifurox
Analogs
Trifurox
Brand Names Mixture
Trifurox
Chemical_Formula
C8H7N3O5
Trifurox
RX_link
http://www.rxlist.com/cgi/generic2/furazol.htm
Trifurox
fda sheet
Trifurox
msds (material safety sheet)
Trifurox
Synthesis Reference
No information avaliable
Trifurox
Molecular Weight
225.158 g/mol
Trifurox
Melting Point
255 oC
Trifurox
H2O Solubility
40 mg/L
Trifurox
State
Solid
Trifurox
LogP
0.691
Trifurox
Dosage Forms
Tablets; Liquid
Trifurox
Indication
For the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
Trifurox
Pharmacology
Furoxone has a broad antibacterial spectrum covering the majority of gastrointestinal tract pathogens including E. coli, staphylococci, Salmonella, Shigella, Proteus, Aerobacter aerogenes, Vibrio cholerae and Giardia lamblia. Its bactericidal activity is based upon its interference with DNA replication and protein production; this antimicrobial action minimizes the development of resistant organisms.
Trifurox
Absorption
Radiolabeled drug studies indicate that furazolidone is well absorbed following oral administration
Trifurox
side effects and Toxicity
Reactions to Furoxone have been reported including a fall in blood pressure, urticaria, fever, arthralgia, and a vesicular morbilliform rash. Other adverse effects can include a brown discoloration of the urine; hemolysis can occur in G6PDH-deficient patients. The drug has a monoamine oxidase (MAO) inhibitory effect and should never be given concurrently to individuals already taking MAO inhibitors.
Trifurox
Patient Information
No information avaliable
Trifurox
Organisms Affected
Microbes (bacteria, parasites)