Carbamohydroxamic Acid en es it fr

Carbamohydroxamic Acid Brand names, Carbamohydroxamic Acid Analogs

Carbamohydroxamic Acid Brand Names Mixture

  • No information avaliable

Carbamohydroxamic Acid Chemical_Formula

CH4N2O2

Carbamohydroxamic Acid RX_link

http://www.rxlist.com/cgi/generic2/hydroxyurea.htm

Carbamohydroxamic Acid fda sheet

Carbamohydroxamic_Acid FDA

Carbamohydroxamic Acid msds (material safety sheet)

Carbamohydroxamic_Acid MSDS

Carbamohydroxamic Acid Synthesis Reference

No information avaliable

Carbamohydroxamic Acid Molecular Weight

76.0547 g/mol

Carbamohydroxamic Acid Melting Point

142-146 oC

Carbamohydroxamic Acid H2O Solubility

1E+006 mg/L

Carbamohydroxamic Acid State

Solid

Carbamohydroxamic Acid LogP

-1.432

Carbamohydroxamic Acid Dosage Forms

Capsule

Carbamohydroxamic Acid Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Carbamohydroxamic Acid Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Carbamohydroxamic Acid Absorption

Well absorbed from the gastrointestinal tract.

Carbamohydroxamic Acid side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Carbamohydroxamic Acid Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Carbamohydroxamic Acid Organisms Affected

Humans and other mammals