Sterile Urea en es it fr

Sterile Urea Brand names, Sterile Urea Analogs

Sterile Urea Brand Names Mixture

  • No information avaliable

Sterile Urea Chemical_Formula

CH4N2O2

Sterile Urea RX_link

http://www.rxlist.com/cgi/generic2/hydroxyurea.htm

Sterile Urea fda sheet

Sterile_Urea FDA

Sterile Urea msds (material safety sheet)

Sterile_Urea MSDS

Sterile Urea Synthesis Reference

No information avaliable

Sterile Urea Molecular Weight

76.0547 g/mol

Sterile Urea Melting Point

142-146 oC

Sterile Urea H2O Solubility

1E+006 mg/L

Sterile Urea State

Solid

Sterile Urea LogP

-1.432

Sterile Urea Dosage Forms

Capsule

Sterile Urea Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Sterile Urea Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Sterile Urea Absorption

Well absorbed from the gastrointestinal tract.

Sterile Urea side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Sterile Urea Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Sterile Urea Organisms Affected

Humans and other mammals