Sterile Urea
Sterile Urea Brand names, Sterile Urea Analogs
- Biosupressin
- Carbamohydroxamic Acid
- Carbamohydroximic Acid
- Carbamohydroxyamic Acid
- Carbamoyl Oxime
- Carbamyl Hydroxamate
- Droxia
- HU
- Hidrix
- Hydrea
- Hydreia
- Hydroxicarbamidum
- Hydroxycarbamide
- Hydroxycarbamine
- Hydroxylurea
- Hydura
- Hydurea
- Idrossicarbamide [Dcit]
- Litaler
- Litalir
- N-Carbamoylhydroxylamine
- N-Hydroxyurea
- Onco-Carbide
- Oxyurea
- Sterile Urea
- Ureaphil
Sterile Urea Brand Names Mixture
- No information avaliable
Sterile Urea Chemical_Formula
CH4N2O2
Sterile Urea RX_link
http://www.rxlist.com/cgi/generic2/hydroxyurea.htm
Sterile Urea fda sheet
Sterile Urea msds (material safety sheet)
Sterile Urea Synthesis Reference
No information avaliable
Sterile Urea Molecular Weight
76.0547 g/mol
Sterile Urea Melting Point
142-146 oC
Sterile Urea H2O Solubility
1E+006 mg/L
Sterile Urea State
Solid
Sterile Urea LogP
-1.432
Sterile Urea Dosage Forms
Capsule
Sterile Urea Indication
For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.
Sterile Urea Pharmacology
Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.
Sterile Urea Absorption
Well absorbed from the gastrointestinal tract.
Sterile Urea side effects and Toxicity
Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg
Sterile Urea Patient Information
HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.
Sterile Urea Organisms Affected
Humans and other mammals
