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Hydura Brand names, Hydura Analogs

Hydura Brand Names Mixture

  • No information avaliable

Hydura Chemical_Formula


Hydura RX_link


Hydura fda sheet

Hydura FDA

Hydura msds (material safety sheet)

Hydura MSDS

Hydura Synthesis Reference

No information avaliable

Hydura Molecular Weight

76.0547 g/mol

Hydura Melting Point

142-146 oC

Hydura H2O Solubility

1E+006 mg/L

Hydura State


Hydura LogP


Hydura Dosage Forms


Hydura Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Hydura Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Hydura Absorption

Well absorbed from the gastrointestinal tract.

Hydura side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Hydura Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Hydura Organisms Affected

Humans and other mammals