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Oxyurea Brand names, Oxyurea Analogs

Oxyurea Brand Names Mixture

  • No information avaliable

Oxyurea Chemical_Formula


Oxyurea RX_link


Oxyurea fda sheet

Oxyurea FDA

Oxyurea msds (material safety sheet)

Oxyurea MSDS

Oxyurea Synthesis Reference

No information avaliable

Oxyurea Molecular Weight

76.0547 g/mol

Oxyurea Melting Point

142-146 oC

Oxyurea H2O Solubility

1E+006 mg/L

Oxyurea State


Oxyurea LogP


Oxyurea Dosage Forms


Oxyurea Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Oxyurea Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Oxyurea Absorption

Well absorbed from the gastrointestinal tract.

Oxyurea side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Oxyurea Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Oxyurea Organisms Affected

Humans and other mammals