Litaler en es it fr

Litaler Brand names, Litaler Analogs

Litaler Brand Names Mixture

  • No information avaliable

Litaler Chemical_Formula


Litaler RX_link

Litaler fda sheet

Litaler FDA

Litaler msds (material safety sheet)

Litaler MSDS

Litaler Synthesis Reference

No information avaliable

Litaler Molecular Weight

76.0547 g/mol

Litaler Melting Point

142-146 oC

Litaler H2O Solubility

1E+006 mg/L

Litaler State


Litaler LogP


Litaler Dosage Forms


Litaler Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Litaler Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Litaler Absorption

Well absorbed from the gastrointestinal tract.

Litaler side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Litaler Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Litaler Organisms Affected

Humans and other mammals