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Droxia Brand names, Droxia Analogs

Droxia Brand Names Mixture

  • No information avaliable

Droxia Chemical_Formula

CH4N2O2

Droxia RX_link

http://www.rxlist.com/cgi/generic2/hydroxyurea.htm

Droxia fda sheet

Droxia FDA

Droxia msds (material safety sheet)

Droxia MSDS

Droxia Synthesis Reference

No information avaliable

Droxia Molecular Weight

76.0547 g/mol

Droxia Melting Point

142-146 oC

Droxia H2O Solubility

1E+006 mg/L

Droxia State

Solid

Droxia LogP

-1.432

Droxia Dosage Forms

Capsule

Droxia Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Droxia Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Droxia Absorption

Well absorbed from the gastrointestinal tract.

Droxia side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Droxia Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Droxia Organisms Affected

Humans and other mammals