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Biosupressin Brand names, Biosupressin Analogs

Biosupressin Brand Names Mixture

  • No information avaliable

Biosupressin Chemical_Formula

CH4N2O2

Biosupressin RX_link

http://www.rxlist.com/cgi/generic2/hydroxyurea.htm

Biosupressin fda sheet

Biosupressin FDA

Biosupressin msds (material safety sheet)

Biosupressin MSDS

Biosupressin Synthesis Reference

No information avaliable

Biosupressin Molecular Weight

76.0547 g/mol

Biosupressin Melting Point

142-146 oC

Biosupressin H2O Solubility

1E+006 mg/L

Biosupressin State

Solid

Biosupressin LogP

-1.432

Biosupressin Dosage Forms

Capsule

Biosupressin Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Biosupressin Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Biosupressin Absorption

Well absorbed from the gastrointestinal tract.

Biosupressin side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Biosupressin Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Biosupressin Organisms Affected

Humans and other mammals