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Hydreia Brand names, Hydreia Analogs

Hydreia Brand Names Mixture

  • No information avaliable

Hydreia Chemical_Formula

CH4N2O2

Hydreia RX_link

http://www.rxlist.com/cgi/generic2/hydroxyurea.htm

Hydreia fda sheet

Hydreia FDA

Hydreia msds (material safety sheet)

Hydreia MSDS

Hydreia Synthesis Reference

No information avaliable

Hydreia Molecular Weight

76.0547 g/mol

Hydreia Melting Point

142-146 oC

Hydreia H2O Solubility

1E+006 mg/L

Hydreia State

Solid

Hydreia LogP

-1.432

Hydreia Dosage Forms

Capsule

Hydreia Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

Hydreia Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

Hydreia Absorption

Well absorbed from the gastrointestinal tract.

Hydreia side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

Hydreia Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

Hydreia Organisms Affected

Humans and other mammals