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N-Carbamoylhydroxylamine Brand names, N-Carbamoylhydroxylamine Analogs

N-Carbamoylhydroxylamine Brand Names Mixture

  • No information avaliable

N-Carbamoylhydroxylamine Chemical_Formula


N-Carbamoylhydroxylamine RX_link


N-Carbamoylhydroxylamine fda sheet

N-Carbamoylhydroxylamine FDA

N-Carbamoylhydroxylamine msds (material safety sheet)

N-Carbamoylhydroxylamine MSDS

N-Carbamoylhydroxylamine Synthesis Reference

No information avaliable

N-Carbamoylhydroxylamine Molecular Weight

76.0547 g/mol

N-Carbamoylhydroxylamine Melting Point

142-146 oC

N-Carbamoylhydroxylamine H2O Solubility

1E+006 mg/L

N-Carbamoylhydroxylamine State


N-Carbamoylhydroxylamine LogP


N-Carbamoylhydroxylamine Dosage Forms


N-Carbamoylhydroxylamine Indication

For management of melanoma, resistant chronic myelocytic leukemia, and recurrent, metastatic, or inoperable carcinoma of the ovary and Sickle-cell anemia.

N-Carbamoylhydroxylamine Pharmacology

Hydroxyurea has dose-dependent synergistic activity with cisplatin in vitro. In vivo Hydroxyurea showed activity in combination with cisplatin against the LX-1 and CALU-6 human lung xenografts, but minimal activity was seen with the NCI-H460 or NCI-H520 xenografts. Hydroxyurea was synergistic with cisplatin in the Lewis lung murine xenograft. Sequential exposure to Hydroxyurea 4 hours before cisplatin produced the greatest interaction.

N-Carbamoylhydroxylamine Absorption

Well absorbed from the gastrointestinal tract.

N-Carbamoylhydroxylamine side effects and Toxicity

Oral, mouse: LD50 = 7330 mg/kg; Oral, rat: LD50 = 5760 mg/kg

N-Carbamoylhydroxylamine Patient Information

HYDREA is a medication that must be handled with care. People who are not taking HYDREA should not be exposed to it. If the powder from the capsule is spilled, it should be wiped up immediately with a damp disposable towel and discarded in a closed container, such as a plastic bag. The medication should be kept away from children and pets.

N-Carbamoylhydroxylamine Organisms Affected

Humans and other mammals