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Sulfona Brand names, Sulfona Analogs

Sulfona Brand Names Mixture

  • No information avaliable

Sulfona Chemical_Formula

C10H10N4O2S

Sulfona RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Sulfona fda sheet

Sulfona msds (material safety sheet)

Sulfona Synthesis Reference

No information avaliable

Sulfona Molecular Weight

250.278 g/mol

Sulfona Melting Point

No information avaliable

Sulfona H2O Solubility

No information avaliable

Sulfona State

Solid

Sulfona LogP

1.883

Sulfona Dosage Forms

Cream

Sulfona Indication

For the treatment of rheumatic fever and meningococcal meningitis

Sulfona Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfona Absorption

No information avaliable

Sulfona side effects and Toxicity

No information avaliable

Sulfona Patient Information

No information avaliable

Sulfona Organisms Affected

Enteric bacteria and other eubacteria