Quadramoid
Brand names,
Quadramoid
Analogs
Quadramoid
Brand Names Mixture
Quadramoid
Chemical_Formula
C10H10N4O2S
Quadramoid
RX_link
http://www.rxlist.com/cgi/generic3/silversulf.htm
Quadramoid
fda sheet
Quadramoid
msds (material safety sheet)
Quadramoid
Synthesis Reference
No information avaliable
Quadramoid
Molecular Weight
250.278 g/mol
Quadramoid
Melting Point
No information avaliable
Quadramoid
H2O Solubility
No information avaliable
Quadramoid
State
Solid
Quadramoid
LogP
1.883
Quadramoid
Dosage Forms
Cream
Quadramoid
Indication
For the treatment of rheumatic fever and meningococcal meningitis
Quadramoid
Pharmacology
Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.
Quadramoid
Absorption
No information avaliable
Quadramoid
side effects and Toxicity
No information avaliable
Quadramoid
Patient Information
No information avaliable
Quadramoid
Organisms Affected
Enteric bacteria and other eubacteria