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Pirimal Brand names, Pirimal Analogs

Pirimal Brand Names Mixture

  • No information avaliable

Pirimal Chemical_Formula

C10H10N4O2S

Pirimal RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Pirimal fda sheet

Pirimal msds (material safety sheet)

Pirimal Synthesis Reference

No information avaliable

Pirimal Molecular Weight

250.278 g/mol

Pirimal Melting Point

No information avaliable

Pirimal H2O Solubility

No information avaliable

Pirimal State

Solid

Pirimal LogP

1.883

Pirimal Dosage Forms

Cream

Pirimal Indication

For the treatment of rheumatic fever and meningococcal meningitis

Pirimal Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Pirimal Absorption

No information avaliable

Pirimal side effects and Toxicity

No information avaliable

Pirimal Patient Information

No information avaliable

Pirimal Organisms Affected

Enteric bacteria and other eubacteria