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Sulfadiazin Brand names, Sulfadiazin Analogs

Sulfadiazin Brand Names Mixture

  • No information avaliable

Sulfadiazin Chemical_Formula

C10H10N4O2S

Sulfadiazin RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Sulfadiazin fda sheet

Sulfadiazin msds (material safety sheet)

Sulfadiazin Synthesis Reference

No information avaliable

Sulfadiazin Molecular Weight

250.278 g/mol

Sulfadiazin Melting Point

No information avaliable

Sulfadiazin H2O Solubility

No information avaliable

Sulfadiazin State

Solid

Sulfadiazin LogP

1.883

Sulfadiazin Dosage Forms

Cream

Sulfadiazin Indication

For the treatment of rheumatic fever and meningococcal meningitis

Sulfadiazin Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfadiazin Absorption

No information avaliable

Sulfadiazin side effects and Toxicity

No information avaliable

Sulfadiazin Patient Information

No information avaliable

Sulfadiazin Organisms Affected

Enteric bacteria and other eubacteria