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Sulfazine Brand names, Sulfazine Analogs

Sulfazine Brand Names Mixture

  • No information avaliable

Sulfazine Chemical_Formula

C10H10N4O2S

Sulfazine RX_link

http://www.rxlist.com/cgi/generic3/silversulf.htm

Sulfazine fda sheet

Sulfazine msds (material safety sheet)

Sulfazine Synthesis Reference

No information avaliable

Sulfazine Molecular Weight

250.278 g/mol

Sulfazine Melting Point

No information avaliable

Sulfazine H2O Solubility

No information avaliable

Sulfazine State

Solid

Sulfazine LogP

1.883

Sulfazine Dosage Forms

Cream

Sulfazine Indication

For the treatment of rheumatic fever and meningococcal meningitis

Sulfazine Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Sulfazine Absorption

No information avaliable

Sulfazine side effects and Toxicity

No information avaliable

Sulfazine Patient Information

No information avaliable

Sulfazine Organisms Affected

Enteric bacteria and other eubacteria