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Diazolone Brand names, Diazolone Analogs

Diazolone Brand Names Mixture

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Diazolone Chemical_Formula


Diazolone RX_link


Diazolone fda sheet

Diazolone msds (material safety sheet)

Diazolone Synthesis Reference

No information avaliable

Diazolone Molecular Weight

250.278 g/mol

Diazolone Melting Point

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Diazolone H2O Solubility

No information avaliable

Diazolone State


Diazolone LogP


Diazolone Dosage Forms


Diazolone Indication

For the treatment of rheumatic fever and meningococcal meningitis

Diazolone Pharmacology

Sulfadiazine is a sulfonamide antibiotic. The sulfonamides are synthetic bacteriostatic antibiotics with a wide spectrum against most gram-positive and many gram-negative organisms. However, many strains of an individual species may be resistant. Sulfonamides inhibit multiplication of bacteria by acting as competitive inhibitors of p-aminobenzoic acid in the folic acid metabolism cycle. Bacterial sensitivity is the same for the various sulfonamides, and resistance to one sulfonamide indicates resistance to all. Most sulfonamides are readily absorbed orally. However, parenteral administration is difficult, since the soluble sulfonamide salts are highly alkaline and irritating to the tissues. The sulfonamides are widely distributed throughout all tissues. High levels are achieved in pleural, peritoneal, synovial, and ocular fluids. Although these drugs are no longer used to treat meningitis, CSF levels are high in meningeal infections. Their antibacterial action is inhibited by pus.

Diazolone Absorption

No information avaliable

Diazolone side effects and Toxicity

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Diazolone Patient Information

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Diazolone Organisms Affected

Enteric bacteria and other eubacteria